abstract：Background:Various clinical trials suggested that risperidone was beneficial in the treatment of autism spectrum disorder (ASD) in children and adolescents. Objective:The aim of this systematic review was to determine the efficacy, acceptability and tolerability of risperidone in the treatment of children and adolesce...

journal_title：Neuropsychiatric disease and treatment

authors： Maneeton N,Maneeton B,Putthisri S,Woottiluk P,Narkpongphun A,Srisurapanont M

更新日期：2018-07-11 00:00:00

abstract：Background:Levodopa-induced dyskinesia (LID) is a troublesome problem in the treatment of Parkinson's disease (PD). The mechanisms of LID are still mysterious. Recently, the interaction between Shp-2 and D1 dopamine receptor (D1R) has been identified to be indispensable in the D1R-mediated extracellular signal-regulate...

journal_title：Neuropsychiatric disease and treatment

authors： Wu N,Wan Y,Song L,Qi C,Liu Z,Gan J

更新日期：2018-07-05 00:00:00

abstract：Objective:Our study aimed to estimate the frequency of inborn errors of metabolism (IEMs) in patients presenting with acute encephalopathy-like picture at an emergency department (ED). Subjects and methods:Our study was a prospective observational study conducted on 30 patients admitted to the pediatric ED with unexpl...

journal_title：Neuropsychiatric disease and treatment

authors： Abdel Maksoud M,ELsayed SM,Shatla RH,Imam AA,Elsayed RM,Mosabah AA,Sherif AM

更新日期：2018-06-29 00:00:00

abstract：Objective:To investigate the effects of sequential nutritional support on nutritional status and immune regulation in patients with early severe traumatic brain injury (STBI). Patients and methods:A total of 62 patients diagnosed with STBI enrolled from Chaoyang Hospital (Beijing, China) from February 2015 to October ...

journal_title：Neuropsychiatric disease and treatment

authors： Jia K,Tong X,Liang F

更新日期：2018-06-14 00:00:00

abstract：Introduction:Night-eating syndrome (NES) involves uncontrolled and most often repeated binge eating during the night. It is related with mood disorders as well as sleep disorders and it may cause obesity. Risks related to NES are obesity, binge eating disorder, bulimia nervosa, affective disorders, and sleep disorders....

journal_title：Neuropsychiatric disease and treatment

authors： Olejniczak D,Bugajec D,Staniszewska A,Panczyk M,Kielan A,Czerw A,Mańczuk M,Juszczyk G,Skonieczna J,Brytek-Matera A

更新日期：2018-06-13 00:00:00

abstract：:Up to 20% of depressed patients demonstrate treatment resistance to one or more adequate antidepressant trials, resulting in a disproportionately high burden of illness. Ketamine is a non-barbiturate, rapid-acting general anesthetic that has been increasingly studied in treatment resistant depression (TRD), typically ...

journal_title：Neuropsychiatric disease and treatment

authors： Jankauskas V,Necyk C,Chue J,Chue P

更新日期：2018-06-06 00:00:00

abstract：Purpose:Individuals with attention deficit/hyperactivity disorder (ADHD) may suffer from emotional dysregulation (ED), although this symptom is not listed among the diagnostic criteria. Methylphenidate (MPH) is useful in reducing emotional symptoms in ADHD. The aim of the present study was to determine both psychosocia...

journal_title：Neuropsychiatric disease and treatment

authors： Suzer Gamli I,Tahiroglu AY

更新日期：2018-05-22 00:00:00

abstract：Purpose:Typically, the diagnosis of conversion motor disorder (CMD) is achieved by the exclusion of a wide range of organic illnesses rather than by applying positive criteria. New diagnostic criteria are highly needed in this scenario. The main aim of this study was to explore the use of behavioral features as an incl...

journal_title：Neuropsychiatric disease and treatment

authors： Pastore A,Pierri G,Fabio G,Ferramosca S,Gigante A,Superbo M,Pellicciari R,Margari F

更新日期：2018-05-18 00:00:00

abstract：Objective:Impairments in emotion regulation, and more specifically in cognitive reappraisal, are thought to play a key role in the pathogenesis of anxiety disorders. However, the available evidence on such deficits is inconsistent. To further illustrate the neurobiological underpinnings of anxiety disorder, the present...

journal_title：Neuropsychiatric disease and treatment

authors： Wang HY,Zhang XX,Si CP,Xu Y,Liu Q,Bian HT,Zhang BW,Li XL,Yan ZR

更新日期：2018-05-09 00:00:00

abstract：Background:It has been suggested that autism spectrum disorder (ASD) might be a "comorbid" condition in selective mutism (SM). Methods:In this retrospective study, we examined medical records of children with SM diagnosis (n=97) at a medical center specializing in assessment of ASD. Results:Mean age for onset of SM s...

journal_title：Neuropsychiatric disease and treatment

authors： Steffenburg H,Steffenburg S,Gillberg C,Billstedt E

更新日期：2018-05-07 00:00:00

abstract：:Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease of the central nervous system, and both T and B cells are involved in its pathogenesis. The vast majority of disease-modifying drugs used for MS act on the inflammatory component of the disease and are approved for use in relapsing-remitting (RR)...

journal_title：Neuropsychiatric disease and treatment

authors： Frau J,Coghe G,Lorefice L,Fenu G,Cocco E

更新日期：2018-04-23 00:00:00

abstract：Purpose:Ginkgo biloba extract (GBE) contains diterpene ginkgolides (DGs), which have been shown to have neuroprotective effects by a number of previous studies. We previously demonstrated part of the action of DG. However, the impact of DG on the prefrontal cortex (PFC) remains unclear. Here, we evaluated the effects o...

journal_title：Neuropsychiatric disease and treatment

authors： Hu Q,Shen P,Bai S,Dong M,Liang Z,Chen Z,Wang W,Wang H,Gui S,Li P,Xie P

更新日期：2018-04-13 00:00:00

abstract：Background:Secondary central nervous system lymphoma (SCNSL) is a rare and aggressive disease, which is defined as secondary central nervous system (CNS) involvement in patients with systemic lymphoma. According to previous reports, SCNSL presents mostly with leptomeningeal spread; however, our experience differs. In t...

journal_title：Neuropsychiatric disease and treatment

authors： Malikova H,Burghardtova M,Koubska E,Mandys V,Kozak T,Weichet J

更新日期：2018-03-12 00:00:00

abstract：Purpose:Paliperidone extended release (ER) is an oral psychotropic treatment formulated to release paliperidone at a controlled, gradually ascending rate. We evaluated the efficacy and safety of switching to paliperidone ER in Taiwanese patients with schizophrenia who were unresponsive or intolerant to previous antipsy...

journal_title：Neuropsychiatric disease and treatment

authors： Chen CY,Tang TC,Chen TT,Bai YM,Tsai HH,Chen HL,Huang CJ,Chen CK,Chen CC,Hsiao MC,Liu CY,Yeh HS,Chiu NY,Hsiao CC,Chen CS,Su TP

更新日期：2018-03-08 00:00:00

abstract：:Psychiatric and physical conditions often coexist, and there is robust evidence that associates the frequency of depression with single and multiple physical conditions. More than half of patients with depression may have at least one chronic physical condition. Therefore, antidepressants are often used in cotherapy w...

journal_title：Neuropsychiatric disease and treatment

authors： Low Y,Setia S,Lima G

更新日期：2018-02-19 00:00:00

abstract：Introduction:The incidence of corpus callosum infarction is low, and sudden cognitive dysfunction caused by corpus callosum infarction is very rare. We report two cases of acute corpus callosum infarction with sudden cognitive impairment, and the related basis, clinical manifestations, diagnosis, differential diagnosis...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang J,Tang Y,Sun Y,Xu Y,Pang L,Li J,Wu T,He M

更新日期：2018-02-13 00:00:00

abstract：Background:Alarming somatic symptoms, in particular, cardiovascular symptoms, are the characteristic feature of panic attacks. Increased cardiac mortality and morbidity have been found in these patients. Power spectral analysis of electrocardiogram R-R intervals is known to be a particularly successful tool in the dete...

journal_title：Neuropsychiatric disease and treatment

authors： Kotianova A,Kotian M,Slepecky M,Chupacova M,Prasko J,Tonhajzerova I

更新日期：2018-02-07 00:00:00

abstract：Purpose:Color preferences vary among normal individuals and psychiatric patients, and this might be related to their different levels of hypnotic susceptibility. We hypothesized that individuals with higher hypnotic susceptibility prefer more arousing colors such as red. Patients and methods:Out of 440 participants, w...

journal_title：Neuropsychiatric disease and treatment

authors： Yu E,Zhu J,Tan Y,Liao Z,Qiu Y,Zhang B,Wang C,Wang W

更新日期：2018-01-30 00:00:00

abstract：Goal:The goal of this study was to explore the impact of self-stigma on the treatment outcomes in patients with anxiety disorders and to find possible mediators of this relationship. Method:Two hundred and nine patients with anxiety disorders, who were hospitalized in a psychotherapeutic department, attended the study...

journal_title：Neuropsychiatric disease and treatment

authors： Ociskova M,Prasko J,Vrbova K,Kasalova P,Holubova M,Grambal A,Machu K

更新日期：2018-01-26 00:00:00

abstract：Background:Early-onset major depressive disorder (EO-MDD), beginning during childhood and adolescence, is associated with more illness burden and a worse prognosis than adult-onset MDD (AO-MDD), but little is known about the neural features distinguishing these subgroup phenotypes. Functional abnormalities of the amygd...

journal_title：Neuropsychiatric disease and treatment

authors： Clark DL,Konduru N,Kemp A,Bray S,Brown EC,Goodyear B,Ramasubbu R

更新日期：2018-01-14 00:00:00

abstract：Aim:This meta-analysis aimed to assess the effect of high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) for the treatment of depression in patients with Parkinson's disease (PD). Methods:The design was a meta-analysis of randomized controlled trials (RCTs). The participants were patients with PD who...

journal_title：Neuropsychiatric disease and treatment

authors： Qin B,Chen H,Gao W,Zhao LB,Zhao MJ,Qin HX,Yang MX

更新日期：2018-01-11 00:00:00

abstract：:Multiple system atrophy is a progressive neurodegenerative disorder that is characterized by autonomic failure, cerebellar ataxia and parkinsonism syndrome in various combinations. In spite of the presence of well-established clinical criteria for multiple system atrophy, ante-mortem diagnosis is difficult. In our cas...

journal_title：Neuropsychiatric disease and treatment

authors： Obelieniene D,Bauzaite S,Kulakiene I,Keleras E,Eitmonaite I,Rastenyte D

更新日期：2018-01-04 00:00:00

abstract：Background:This was a longitudinal study which investigated the relationship between serum uric acid (SUA) and total bilirubin (Tbil) upon admission in elderly stroke patients and the occurrence of postischemic stroke depression (IPSD) at 3, 6, and 9 months of post-stroke follow-up. Subjects and methods:Data were anal...

journal_title：Neuropsychiatric disease and treatment

authors： Gao J,Xu W,Han K,Zhu L,Gao L,Shang X

更新日期：2017-12-27 00:00:00

abstract：:Elevation of plasma inflammatory factors in major depressive disorder (MDD) has been repeatedly observed, but contradictory results have also been reported. Alteration of complement components in MDD may also contribute to the pathophysiology of MDD by participating in inflammation. The recent findings that complement...

journal_title：Neuropsychiatric disease and treatment

authors： Wei J,Liu Y,Zhao L,Yang X,Ni P,Wang Y,Li T,Ma X

更新日期：2017-12-20 00:00:00

abstract：Aim:Cardiovascular risk factors are also risk factors for cognitive impairment. They have cumulative effect in target organ damage. The precise correlation between cardiovascular risk factors and cognitive impairment, as well as assessing the extent to which they may affect cognitive functioning, is difficult to ascert...

journal_title：Neuropsychiatric disease and treatment

authors： Yaneva-Sirakova T,Traykov L,Petrova J,Gruev I,Vassilev D

更新日期：2017-12-05 00:00:00

abstract：Objective:Ser9Gly (rs6280) is a functional single-nucleotide polymorphism (SNP) in the dopamine receptor D3 (DRD3) gene that may be associated with schizophrenia. We performed a meta-analysis to determine whether Ser9Gly influences the risk of schizophrenia and examined the relationship between the Ser9Gly SNP and the ...

journal_title：Neuropsychiatric disease and treatment

authors： Qi XL,Xuan JF,Xing JX,Wang BJ,Yao J

更新日期：2017-11-23 00:00:00

abstract：Objective:Many previous studies have demonstrated that neuromyelitis optica (NMO) patients have abnormalities of brain anatomy and function. However, differences in spontaneous brain activity between myelin oligodendrocyte glycoprotein (MOG)-IgG ON and aquaporin 4(AQP4)-neuromyelitis optica-optic neuritis (ON) remain u...

journal_title：Neuropsychiatric disease and treatment

authors： Wang J,Tian Y,Shao Y,Feng H,Qin L,Xu W,Liu H,Xu Q,Wei S,Ma L

更新日期：2017-10-24 00:00:00

abstract：:Major depressive disorder (MDD) and Parkinson's disease (PD) share symptoms such as tremor. Bupropion, a norepinephrine-dopamine reuptake inhibitor, shows weak dopamine transporter (DAT) occupancy. We report here on a patient with MDD whose hand tremors might have been misdiagnosed as PD by single-photon emission comp...

journal_title：Neuropsychiatric disease and treatment

authors： Lin CH,Lane HY

更新日期：2017-10-19 00:00:00

abstract：OBJECTIVE:Cognitive theory assumes a pivotal role of negative core beliefs about the self in dysfunctional attitudes predisposing to depression. Meanwhile, the role of positive core beliefs about the self in cognitive vulnerability to depression is unknown. Therefore, we examined the relationship of negative and positi...

journal_title：Neuropsychiatric disease and treatment

authors： Otani K,Suzuki A,Matsumoto Y,Shirata T

更新日期：2017-10-12 00:00:00

abstract：BACKGROUND:Depressive symptoms are significant and very common psychiatric complications in patients with Alzheimer's disease (AD), which can aggravate the decline in social function. However, changes in the functional connectivity (FC) of the brain in AD patients with depressive symptoms (D-AD) remain unclear. OBJECT...

journal_title：Neuropsychiatric disease and treatment

authors： Zhang J,Guo Z,Liu X,Jia X,Li J,Li Y,Lv D,Chen W

更新日期：2017-10-11 00:00:00

abstract：BACKGROUND:Stroke has high mortality and morbidity. Biomarkers are required for to predict stroke outcomes, which could help clinicians to provide rationale approaches for patient management. The dynamic changes in circulating immune cells have been reported in stroke patients and animal models of stroke. AIM:The aim ...

journal_title：Neuropsychiatric disease and treatment

authors： Wang Y,Liu J,Wang X,Liu Z,Li F,Chen F,Geng X,Ji Z,Du H,Hu X

更新日期：2017-10-03 00:00:00

abstract：:Medically intractable epilepsy is associated with increased morbidity and mortality. For those with focal epilepsy and correlated electrophysiological or radiographic features, open surgical resection can achieve high rates of seizure control, but can be associated with neurologic deficits and cognitive effects. Recen...

journal_title：Neuropsychiatric disease and treatment

authors： Shukla ND,Ho AL,Pendharkar AV,Sussman ES,Halpern CH

更新日期：2017-09-26 00:00:00

abstract：:The history and present status of the definition, prevalence, neurobiology, and treatment of atypical depression (AD) is presented. The concept of AD has evolved through the years, and currently, in Diagnostic and Statistical Manual of Mental Disorders (DSM), Fifth Edition, the specifier of depressive episode with aty...

journal_title：Neuropsychiatric disease and treatment

authors： Łojko D,Rybakowski JK

更新日期：2017-09-20 00:00:00

abstract：BACKGROUND:In Japan, the effects of reduced water, such as hydrogen-rich electrolyzed reduced water and natural reduced water, like Hita Tenryosui water®, have been examined. The purpose of the present study was to identify the role of natural reduced water in anxiety and blood biochemical analysis. MATERIALS AND METH...

journal_title：Neuropsychiatric disease and treatment

authors： Masuda K,Tanaka Y,Kanehisa M,Ninomiya T,Inoue A,Higuma H,Kawashima C,Nakanishi M,Okamoto K,Akiyoshi J

更新日期：2017-09-08 00:00:00

abstract：INTRODUCTION:Antipsychotics are recommended as first-line therapy for acute mania and maintenance treatment of bipolar disorder; however, published literature suggests their real-world use remains limited. Understanding attitudes toward these medications may help identify barriers and inform personalized therapy. This ...

journal_title：Neuropsychiatric disease and treatment

authors： Sajatovic M,DiBiasi F,Legacy SN

更新日期：2017-08-30 00:00:00

abstract：:Quetiapine is an atypical antipsychotic agent which is also prescribed for delirium due to its anti-dopaminergic effects; aphasia is an unusual side effect associated with the drug. Here, we report the case of an 83-year-old woman who was prescribed quetiapine (50 mg per day) for delirium. Unexpected, global aphasia o...

journal_title：Neuropsychiatric disease and treatment

authors： Chien CF,Huang P,Hsieh SW

更新日期：2017-08-28 00:00:00

abstract：OBJECTIVES:Depressive symptoms are common among patients with obesity. Abnormalities in dopamine signaling involved in the reward circuit may ensue excessive consumption of food, resulting in obesity and leading to neuropsychiatric disorders such as depression. This study sought to investigate the association of polymo...

journal_title：Neuropsychiatric disease and treatment

authors： Bieliński M,Jaracz M,Lesiewska N,Tomaszewska M,Sikora M,Junik R,Kamińska A,Tretyn A,Borkowska A

更新日期：2017-08-18 00:00:00

abstract：OBJECTIVE OF THE STUDY:To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in full-term newborns with hypoxic ischemic encephalopathy (HIE). PATIENTS AND METHODS:A case-control study including 25 full-term new-born ...

journal_title：Neuropsychiatric disease and treatment

authors： Alkholy UM,Abdalmonem N,Zaki A,Ali YF,Mohamed SA,Abdelsalam NI,Hashim MIA,Sekkien MA,Elsherbiny YM

更新日期：2017-08-08 00:00:00

abstract：OBJECTIVE:To examine how clinical and demographic patient baseline characteristics influence effectiveness of duloxetine versus selective serotonin reuptake inhibitor (SSRI) treatment, in real-world Japanese clinical settings of patients with major depressive disorder (MDD) and associated painful physical symptoms (PPS...

journal_title：Neuropsychiatric disease and treatment

authors： Kuga A,Tsuji T,Hayashi S,Fujikoshi S,Tokuoka H,Yoshikawa A,Escobar R,Tanaka K,Azekawa T

更新日期：2017-08-04 00:00:00

abstract：OBJECTIVE:To explore the abnormal intrinsic functional hubs in alcohol dependence using voxelwise degree centrality analysis approach, and their relationships with clinical features. MATERIALS AND METHODS:Twenty-four male alcohol dependence subjects free of medicine (mean age, 50.21±9.62 years) and 24 age- and educati...

journal_title：Neuropsychiatric disease and treatment

authors： Luo X,Guo L,Dai XJ,Wang Q,Zhu W,Miao X,Gong H

更新日期：2017-07-28 00:00:00